Anatomical Sciences (AS)

Medical Gross Anatomy is the study of the body's structure. The course is organized by the four major body regions: upper limb; back and lower limb; thorax, abdomen and pelvis; and head and neck.

Computer-aided instruction will be used to help students learning anatomy. The student is expected to learn anatomical terminology, three- dimensional, radiological, and live (palpatory) anatomy.

Throughout the course students will be challenged to relate the anatomy to solving clinical problems. The latter is an integral part of the anatomy curriculum. Students will be evaluated by a series of four written examinations. Course available to Master of Science degree-seeking students only.

Medical Histology is designed to give students a foundation of the basic structural and functional organization of cells and tissues in the human body. Histology focuses on the histologic study and microscopic anatomy of basic tissue types. The understanding of the normal histology presented in this course is critical for the student's ability to: (1) envision the cellular/tissue structures associated with the biochemical and physiological processes explained in other courses, and (2) identify and comprehend the abnormal histology present in Pathology. Pre-Requisites: Admission to the Master of Science, Biomedical Professions or Anatomical Sciences Program. Offered as an elective when available.

This unit provides an understanding of the basic anatomy of the head and neck, thorax, abdomen and pelvis, as well as the limbs. Radiographic images, cross-sectional imaging software, and diagrams are used to support the learning process.

This course focuses on clinically-oriented human development from gametogenesis to birth. The first section of the course emphasizes developmental processes and early development of the embryo and fetus. The second section of the course emphasizes organ system development. Both sections will incorporate developmental genetics and clinical case vignettes to explain normal and abnormal development. Emphasis is placed on anatomical change with discussion of developmental mechanisms and physiology. This in-depth look at embryology will provide a more profound understanding of human anatomy. Pre-requisite: ANAT 501

A graduate level course designed for the continued study of medical gross anatomy by method of full human dissection. Students will begin with basic dissection techniques and advance to more detailed methods. All sections of human anatomy will be covered - limbs, back, thorax, abdomen, pelvis, neck and head. Evaluation will be based on a performance grading rubric. Pre-Requisite: LMU-DCOM Masters Student status; successful completion of ANAT 501 Gross Anatomy, or by permission of instructor. 

This course will provide an advanced focus on 1) biomolecles (amino adis, protein structure and folding, protein function iwth emphasis on hemoglobin and myoglobin, carbohydrate, lipid and membrane structure and function); 2)enzyme kinectics and regulation of enzyme activity; and 3)metabolism of carbohydrates, lipids, amino acids and nucleotides. Each will be related to theme of regulation and integration of these metabolic pathways and how they differ tin the muscle and the liver. Students are expected to present and discuss at least one recent paper from the primary literature relevant to the course topics. Pre-requisites: Admission to the Master of Science program and satisfactory completion of an upper-level undergraduate biochemistry course.

This course is an in-depth coverage of Eukaryotic and Prokaryotic molecular cell biology. Topics include structure and utilization of the organismal genome; nuclear and cytoplasmic division; membrane structure, transport, and compartment dynamics; cell communication; cell-cycle regulation; cytoskeletal structure and dynamics; cellular aspects of multicellular development and apoptosis. Assigned readings in current primary literature will be used to extend learning of topics in this course. This course has a required critical analysis paper.

This course will address light, electron, atomic force, and confocal microscopy as complimentary study methods. The history of microscopy will allow comparison and contrasts of light and electron optics. The focus of the course will be on advanced imaging techniques, especially electron microscopy. Electron paths will be followed from filament generation of primary electrons, focusing electrons through the column, to specimen interactions generating secondary and backscattered electrons, and X-rays. Techniques will include sample fixation, dehydration, mounting, coating and storage for high and low vacuum systems. A discussion of X-ray microanalysis will show the quantitative side of advanced imaging. Students will gain hands-on experience with scanning electron microscopy. This course has complimentary lecture and lab assignments. Pre-Requisities: Admission to the Master of Science program.

This course is an in-depth coverage of vertebrate physiology. Study will include the specific function of all major vertebrate organ systems along with focus on neurological and endocrine regulatory integration. Assigned readings in current primary literature will be used to extend learning of topics in this course. This course has a required critical analysis paper.

This course covers the principles and applications of research design in the life sciences. This includes framing and articulating a research question, creating testable hypotheses, collecting valid data, approaches to data analyses, and presentation of results. Examples from the primary literature will be discussed and evaluated.

This course focuses on formal scientific writing. It emphasizes concise communication of the research process. It includes both written and oral presentations of previous relevant background studies, statement of the research question, detailing of materials and methods, linkage of claims, warrants, and evidence, and concluding discussions. A written research proposal draft is required for completion of this course. Pre-Requisites: LSCI 604 is a pre-requisite for the LSR degree. LSCI 604 is not a pre-requisite for the AS and BMS degrees. 

Applied Ethics is the inquiry from the standpoint of moral philosophy into practical decision making. The focus of the course will concern ethical issues in relation to research and practice in the biomedical sciences. The course's instructional format will include a combination of lecture, video, small group discussion, and seminar. It will also include independent study of a focused topic selected by the student in consultation with their supervisor. The course will be primarily "Case Based" covering a range of topics with the emphasis on ethical decision-making. Ethical theory will be discussed in relation to making the most reasoned and informed argument for practical courses of action. Special attention will be given to the ethical dimensions of research involving human and non-human subjects. Pre-Requisites: Admission into the Master of Science Program and at least one prior undergraduate course in ethics.

This course is designed for students who have background knowledge in immunology. This course will investigate the immune response and its involvement in health and disease through the use of case studies, webinars, and literature reviews. Topic areas covered include, but are not limited to, innate and adaptive immunity, regulation of the immune system, induction and role of cell types and subsets, transplant immunology, immuno-pathologies, tumor immunology, and immunotherapies. Pre-Requisites: Admission to the Master of Science program.

This introductory course covers key pharmacologic concepts related to the physiologic, cellular, and biochemical actions of major drug classes used in human medicine. Students will learn basic scientific concepts including the theoretical basis of pharmacodynamics and pharmacokinetics as well as the molecular and physiologic actions of drugs that influence function of the autonomic nervous system, the somatic nervous system, the central nervous system, the cardiopulmonary/renal systems, the endocrine system, the immune system, and actions of drugs that target microbial infection. In addition, students will apply pharmacologic principles to understand impact of drugs of abuse, important drug interactions, and actions of dietary/botanical supplements. Prerequisites: Admission to the Master of Science program

This course will introduce basic principles and then apply those principles to clinical relevance. All aspects of microbiology will be explored. This course will cover taxonomy, metabolism, pathogenesis, modes of transmission, epidemiology, methods of isolation and control for pathogenic bacteria, viruses, fungi and parasites. This course will include etiological agents responsible for many infectious diseases that future practitioners would encounter.

This course will cover the basic methods for infectious diseases epidemiology. Emphasis will be on definitions, outbreak investigations, disease surveillance, dynamic of transmission, effectiveness of vaccines, and diagnostics across species. The case studies will focus on diarrheal diseases, hepatitis, HIV, sexually transmitted diseases, parasitic diseases, and other vector-borne diseases. The course will also cover One Health and the connectivity of human, animal and environment.

Explores effective communication in health care. Various techniques will be considered in finding better ways to have discussions with colleagues and consultations with patients. This will include written and verbal communication in the various ways these now occur. The course will focus on special considerations in communication among the diverse populations of people with whom medical professionals can expect to interact. An important facet of this exploration is that the range of cultural norms in communities requires an understanding that the rich diversity is to be appreciated and respected.

This course provides an analysis of curriculum development and methods for aligning course content to goals and evaluation procedures. The philosophical, historical, and psychological foundations of curriculum will be explored to help students better understand how curriculum models might be utilized in an ever changing and emerging educational environment. Topics explored will include course organization, teaching strategies/methods in the biological science classroom, preparing educational units, developing the laboratory content, teaching methods, learning styles, etc.

This course will introduce students to the concept of health equity and will provide a broad overview of health disparities in the United States. We will examine historical issues and empirical data, analyzing the experience of patients and providers. We will look at relevant research and consider interventions to promote health equity through a combination of readings, lectures, reflection papers, and in-class discussion. Our focus will be on social, genetic, economic, environmental, and cultural factors that contribute to differences in morbidity and mortality.

Various specific life sciences topics are covered which include in-depth presentation, analysis and discussion of the related primary literature. May be repeated with a different topic. Pre-Requisites: Admission to the Master of Science program and permission of instructor.

The graduate student conducts life science research under the supervision of a graduate research mentor. A written research report is required to complete the course. May be repeated for credit.